Organotin(IV) Carboxylates of Substituted α-Cinnamic Acid, RnSn(OCOC(R2)=CHR1)4 – n: Synthesis, Spectroscopic Characterization and Biological Evaluation
Sadiq-ur-Rehman
Department of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, 13100 Pakistan
Search for more papers by this authorCorresponding Author
Bilal Ahmad Khan
Department of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, 13100 Pakistan
Correspondence to: Bilal Ahmad Khan; e-mail: [email protected].Search for more papers by this authorMuhammad Aziz Chaudhary
Chemistry Department, Mirpur University of Science and Technology, Mirpur, Pakistan
Search for more papers by this authorKhawaja Ansar Yasin
Department of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, 13100 Pakistan
Search for more papers by this authorSaqib Ali
Chemistry Department, Quaid-i-Azam University, Islamabad, 45320 Pakistan
Search for more papers by this authorSadiq-ur-Rehman
Department of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, 13100 Pakistan
Search for more papers by this authorCorresponding Author
Bilal Ahmad Khan
Department of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, 13100 Pakistan
Correspondence to: Bilal Ahmad Khan; e-mail: [email protected].Search for more papers by this authorMuhammad Aziz Chaudhary
Chemistry Department, Mirpur University of Science and Technology, Mirpur, Pakistan
Search for more papers by this authorKhawaja Ansar Yasin
Department of Chemistry, The University of Azad Jammu and Kashmir, Muzaffarabad, 13100 Pakistan
Search for more papers by this authorSaqib Ali
Chemistry Department, Quaid-i-Azam University, Islamabad, 45320 Pakistan
Search for more papers by this authorABSTRACT
Di- and triorganotin(IV) carboxylates, RnSn(OCOC(R2)=CHR1)4–n (n = 2 and 3; R = Me, Et, n-Bu, Ph; R1 = 3-CH3O-4-OHC6H3, R2 = C6H5) were prepared by reacting the corresponding organotin(IV) chloride with the silver salt of the (E)-3-(4-hydroxy-3-methoxyphenyl)-2-phenylpropenoic acid. The title compounds were investigated and characterized by elemental analysis, infrared (FT-IR), multinuclear (1H, 13C, 119Sn) NMR, and mass spectrometry, and possible structures were proposed. The complexes and ligand acid (HL) have been evaluated in vitro against various bacteria and fungi. The results noticed during the biocidal activity screenings proved their in vitro biological potential. They were also tested for cytotoxicity.
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