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α-Aminophosphonates and α-Aminophosphine Oxides by the Microwave-Assisted Kabachnik–Fields Reactions of 3-Amino-6-methyl-2 H-pyran-2-ones

Erika Bálint

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

Research Group of the Hungarian Academy of Sciences, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

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Judit Takács,

Judit Takács

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

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László Drahos,

László Drahos

Hungarian Academy of Sciences, Chemical Research Center, 1525 Budapest, Hungary

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Amadej Juranovič,

Amadej Juranovič

Faculty of Chemistry and Chemical Technology, University of Ljubljana, 1000 Ljubljana, Slovenia

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Marijan Kočevar,

Marijan Kočevar

Faculty of Chemistry and Chemical Technology, University of Ljubljana, 1000 Ljubljana, Slovenia

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György Keglevich,

Corresponding Author

György Keglevich

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

Correspondence to: György Keglevich; e-mail: [email protected].Search for more papers by this author

Erika Bálint,

Erika Bálint

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

Research Group of the Hungarian Academy of Sciences, Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

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Judit Takács,

Judit Takács

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

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László Drahos,

László Drahos

Hungarian Academy of Sciences, Chemical Research Center, 1525 Budapest, Hungary

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Amadej Juranovič,

Amadej Juranovič

Faculty of Chemistry and Chemical Technology, University of Ljubljana, 1000 Ljubljana, Slovenia

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Marijan Kočevar,

Marijan Kočevar

Faculty of Chemistry and Chemical Technology, University of Ljubljana, 1000 Ljubljana, Slovenia

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György Keglevich,

Corresponding Author

György Keglevich

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary

Correspondence to: György Keglevich; e-mail: [email protected].Search for more papers by this author

First published: 10 April 2013

https://doi.org/10.1002/hc.21086

Citations: 32

Contract grant sponsor: Slovenian–Hungarian Scientific Research program.

Contract grant numbers: BI-HU/11-12-005 and 2011-0637.

Contract grant sponsor: Hungarian Scientific Research Fund.

Contract grant numbers: OTKA K83118 and TÁMOP-4.2.2.B-10/1-2010-0009.

Contract grant sponsor: Slovenian Research Agency.

Contract grant number: P1-0230-0103.

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ABSTRACT

The microwave-assisted Kabachnik–Fields reaction of a series of 3-amino-6-methyl-2H-pyran-2-ones, paraformaldehyde, and dialkyl phosphites or diphenylphosphine oxide led to α-aminophosphonates or α-aminophosphine oxides, respectively. The α‑aminophosphonates were obtained under solvent-free conditions, whereas the α‑aminophosphine oxides in acetonitrile. The novel products were characterized by NMR and mass spectral data. © 2013 Wiley Periodicals, Inc. Heteroatom Chem 24:221–225, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.21086

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α-Aminophosphonates and α-Aminophosphine Oxides by the Microwave-Assisted Kabachnik–Fields Reactions of 3-Amino-6-methyl-2 H-pyran-2-ones

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α-Aminophosphonates and α-Aminophosphine Oxides by the Microwave-Assisted Kabachnik–Fields Reactions of 3-Amino-6-methyl-2 H-pyran-2-ones

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