Volume 24, Issue 3 pp. 234-241

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Dioxirane Oxidation of 2-Aryl-1-vinyl-1, 1-diphosphane Dioxide: A Convenient Approach for the Synthesis of Novel 1,2-Epoxy-2-aryl Ethylgembisphosphonates

Marthe Carine Djuidje Fotsing,

Marthe Carine Djuidje Fotsing

Department of Applied Chemistry, University of Johannesburg, Doornfontein Campus, Johannesburg, 2028 South Africa

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Neil Coville,

Neil Coville

Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, Johannesburg, 2050 South Africa

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Xavier Yangkou Mbianda,

Corresponding Author

Xavier Yangkou Mbianda

Department of Applied Chemistry, University of Johannesburg, Doornfontein Campus, Johannesburg, 2028 South Africa

Correspondence to: X. Y. Mbianda; e-mail: [email protected].Search for more papers by this author

Marthe Carine Djuidje Fotsing,

Marthe Carine Djuidje Fotsing

Department of Applied Chemistry, University of Johannesburg, Doornfontein Campus, Johannesburg, 2028 South Africa

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Neil Coville,

Neil Coville

Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, Johannesburg, 2050 South Africa

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Xavier Yangkou Mbianda,

Corresponding Author

Xavier Yangkou Mbianda

Department of Applied Chemistry, University of Johannesburg, Doornfontein Campus, Johannesburg, 2028 South Africa

Correspondence to: X. Y. Mbianda; e-mail: [email protected].Search for more papers by this author

First published: 27 March 2013

https://doi.org/10.1002/hc.21084

Citations: 6

Contract grant sponsor: Organization for Women in Science for the Developing World.

Contract grant sponsor: National Research Foundation.

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ABSTRACT

The synthesis of tetraethyl 1,2-epoxy-2-aryl ethylgembisphosphonates by direct epoxidation of 2-aryl,vinyl-1,1-diphosphonate derivatives with ethyl methyldioxirane generated in situ from potassium hydrogen monopersulfate (caroate) and butanone in a phase transfer system is reported. The epoxides were isolated in excellent yields and fully characterized by spectral and microanalytical data. © 2013 Wiley Periodicals, Inc. Heteroatom Chem 24:234–241, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.21084

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Dioxirane Oxidation of 2-Aryl-1-vinyl-1, 1-diphosphane Dioxide: A Convenient Approach for the Synthesis of Novel 1,2-Epoxy-2-aryl Ethylgembisphosphonates

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Dioxirane Oxidation of 2-Aryl-1-vinyl-1, 1-diphosphane Dioxide: A Convenient Approach for the Synthesis of Novel 1,2-Epoxy-2-aryl Ethylgembisphosphonates

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