New Supramolecular Triorganotin(IV) Dithiocarboxylates as Potential Antibacterial Agents

Four triorganotin derivatives of general formula C₁₀H₁₀NS₂SnR₃,_, where R = CH₃ (1), C₄H₉ (2), C₆H₁₁ (3), and C₆H₅ (4), have been synthesized by the metathesis reaction of 1,2,3,4-tetrahydroisoquinolnium salt of ligand with triorganotin(IV) chloride in the 1:1 ratio. These complexes were characterized by elemental analysis, Raman, IR, multinuclear NMR (¹H, ¹³C, and ¹¹⁹Sn), and mass spectrometry. The crystal structure confirmed a supramolecular zig-zag chain structure mediated by S–H (2.968 Å) for complex 4 with the central Sn atom exists in a distorted trigonal bipyramidal geometry. A subsequent antibacterial study indicates that the compounds are biologically active.