Reactions with 3,6-diaminothieno[2,3-b]-pyridines: Synthesis and characterization of several new fused pyridine heterocycles
Corresponding Author
Mohamed A. M. Gad-Elkareem
Department of Chemistry, Faculty of Science, Al-Azhar University (Assiut branch), Assiut 71524, A. R. Egypt
Department of Chemistry, Faculty of Science, Al-Azhar University (Assiut branch), Assiut 71524, A. R. EgyptSearch for more papers by this authorMohamed A. A. Elneairy
Department of Chemistry, Faculty of Science, Cairo University, Giza, A. R. Egypt
Search for more papers by this authorAdel M. Taha
Department of Chemistry, Faculty of Science, Cairo University, Giza, A. R. Egypt
Search for more papers by this authorCorresponding Author
Mohamed A. M. Gad-Elkareem
Department of Chemistry, Faculty of Science, Al-Azhar University (Assiut branch), Assiut 71524, A. R. Egypt
Department of Chemistry, Faculty of Science, Al-Azhar University (Assiut branch), Assiut 71524, A. R. EgyptSearch for more papers by this authorMohamed A. A. Elneairy
Department of Chemistry, Faculty of Science, Cairo University, Giza, A. R. Egypt
Search for more papers by this authorAdel M. Taha
Department of Chemistry, Faculty of Science, Cairo University, Giza, A. R. Egypt
Search for more papers by this authorAbstract
6-Aminopyridine-2(1H)thiones 1 reacting with α-halo-compounds 2a–c afforded the alkylthiopyridine derivatives 3a–c which in turn cyclized to the corresponding thieno[2,3-b]pyridine derivatives 4a–c. Several thieno[2,3-b]pyridine derivatives 7, 16, 19, pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine derivatives 6a,b, 11a–c, 21 and pyrido[3′,2′:4,5]thieno[3,2-c]pyridazine derivatives 13, 17 were prepared starting from compounds 4a–c. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:405–413, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20313
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