Volume 10, Issue 6 pp. 539-544
Genetic Analysis of Multiple Quantitative Risk Factors for Complex Disease
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Correlation analysis of twin data with repeated measures based on generalized estimating equations

Dr. John S. Grove

Corresponding Author

Dr. John S. Grove

Biostatistics Program, School of Public Health, University of Hawaii, Honolulu

Biostatistics Program, University of Hawaii School of Public Health, Honolulu, HI 96826Search for more papers by this author
Lue Ping Zhao

Lue Ping Zhao

Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii

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Filemon Quiaoit

Filemon Quiaoit

Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii

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First published: 1993
Citations: 8

Abstract

Repeated measures allow additional tests of common assumptions in twin correlation analysis. Analysis of log serum triglyceride level in NHLBI male twins using generalized estimating equations disclosed that the mean and variance shifted across exams, presumably because of changes in laboratory practice. © 1993 Wiley-Liss, Inc.

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