Volume 15, Issue 7 e70408
COMMENTARY
Open Access

The coming of age of DNA-based catalysts for therapeutic applications

Robert Hesse

Robert Hesse

Faculty of Mathematics and Natural Sciences, Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany

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Christoph G. W. Gertzen

Christoph G. W. Gertzen

Faculty of Mathematics and Natural Sciences, Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany

Faculty of Mathematics and Natural Sciences, Center for Structural Studies, Heinrich Heine University, Düsseldorf, Germany

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Jessica Felice Schmuck

Jessica Felice Schmuck

Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany

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Justin Darvin Böcker

Justin Darvin Böcker

Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany

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Piyush Pandey

Piyush Pandey

Department of Molecular Medicine II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany

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Tobias Behn

Tobias Behn

Department of Chemistry, Institute of Organic Chemistry, University of Cologne, Cologne, Germany

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Christopher Ruth

Christopher Ruth

Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany

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Detlev Riesner

Detlev Riesner

Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany

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Stephanie Kath-Schorr

Corresponding Author

Stephanie Kath-Schorr

Department of Chemistry, Institute of Organic Chemistry, University of Cologne, Cologne, Germany

Correspondence

Stephanie Kath-Schorr, Department of Chemistry, Institute of Organic Chemistry, University of Cologne, Cologne, Germany.

Email: [email protected]

Philipp Lang, Department of Molecular Medicine II, University Hospital Düsseldorf, Dusseldorf, Germany.

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Holger Gohlke, Faculty of Mathematics and Natural Sciences, Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany.

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Manuel Etzkorn, Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany.

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Philipp A. Lang

Corresponding Author

Philipp A. Lang

Department of Molecular Medicine II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany

Correspondence

Stephanie Kath-Schorr, Department of Chemistry, Institute of Organic Chemistry, University of Cologne, Cologne, Germany.

Email: [email protected]

Philipp Lang, Department of Molecular Medicine II, University Hospital Düsseldorf, Dusseldorf, Germany.

Email: [email protected]

Holger Gohlke, Faculty of Mathematics and Natural Sciences, Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany.

Email: [email protected]

Manuel Etzkorn, Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany.

Email: [email protected]

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Holger Gohlke

Corresponding Author

Holger Gohlke

Faculty of Mathematics and Natural Sciences, Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany

Institute of Bio- and Geosciences (IBG-4: Bioinformatics), Forschungszentrum Jülich, Jülich, Germany

Correspondence

Stephanie Kath-Schorr, Department of Chemistry, Institute of Organic Chemistry, University of Cologne, Cologne, Germany.

Email: [email protected]

Philipp Lang, Department of Molecular Medicine II, University Hospital Düsseldorf, Dusseldorf, Germany.

Email: [email protected]

Holger Gohlke, Faculty of Mathematics and Natural Sciences, Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany.

Email: [email protected]

Manuel Etzkorn, Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany.

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Manuel Etzkorn

Corresponding Author

Manuel Etzkorn

Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany

Institute of Biological Information Processing (IBI-7), Forschungszentrum Jülich, Jülich, Germany

Correspondence

Stephanie Kath-Schorr, Department of Chemistry, Institute of Organic Chemistry, University of Cologne, Cologne, Germany.

Email: [email protected]

Philipp Lang, Department of Molecular Medicine II, University Hospital Düsseldorf, Dusseldorf, Germany.

Email: [email protected]

Holger Gohlke, Faculty of Mathematics and Natural Sciences, Institute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany.

Email: [email protected]

Manuel Etzkorn, Faculty of Mathematics and Natural Sciences, Institute of Physical Biology, Heinrich Heine University, Düsseldorf, Germany.

Email: [email protected]

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First published: 14 July 2025
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CONFLICT OF INTEREST STATEMENT

The authors declare no conflicts of interest.

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