Concise Report
Electrochemical Selective Oxidative Synthesis of Diversified Sulfur Heterocycles from β-Ketothioamides
Li-Rong Wen,
Ning-Ning Wang,
Wu-Bo Du,
Ming-Zhe Zhu,
Chao Pan,
Lin-Bao Zhang,
Ming Li,
Li-Rong Wen
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorNing-Ning Wang
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorWu-Bo Du
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorMing-Zhe Zhu
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorChao Pan
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorCorresponding Author
Lin-Bao Zhang
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
E-mail: [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Ming Li
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
E-mail: [email protected]; [email protected]Search for more papers by this authorLi-Rong Wen,
Ning-Ning Wang,
Wu-Bo Du,
Ming-Zhe Zhu,
Chao Pan,
Lin-Bao Zhang,
Ming Li,
Li-Rong Wen
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorNing-Ning Wang
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorWu-Bo Du
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorMing-Zhe Zhu
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorChao Pan
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
Search for more papers by this authorCorresponding Author
Lin-Bao Zhang
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
E-mail: [email protected]; [email protected]Search for more papers by this authorCorresponding Author
Ming Li
State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science & Technology, Qingdao, Shandong, 266042 China
E-mail: [email protected]; [email protected]Search for more papers by this authorMain observation and conclusion
A general and practical protocol for the construction of diversified sulfur heterocycles has been described through organic electrosynthesis means. In undivided cell, dihydrothiophenes, thiazolines and 1,4-dithiines could be easily generated from various available β-ketothioamides under metal-free and external oxidant-free conditions. The transformation underwent smoothly under mild conditions and could be easily scaled-up. Moreover, different sulfur heterocycles were generated through varying solvent and 1,4-diazabicyclo[2.2.2]octane (DABCO) could enable the hydrogen atom transfer (HAT) process of this transformation.
Supporting Information
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Appendix S1: Supporting Information |
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