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A Green Route for the One-Pot Synthesis of 1,2-Disubstituted Benzimidazoles Using Iron(III) Phosphate under Solventless Conditions
F. K. Behbahani,
Parisa Ziaei,
Corresponding Author
F. K. Behbahani
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran, Tel.: 0098-0261-4418145; Fax: 0098-0261-4418156Search for more papers by this authorParisa Ziaei
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran
Search for more papers by this authorF. K. Behbahani,
Parisa Ziaei,
Corresponding Author
F. K. Behbahani
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran, Tel.: 0098-0261-4418145; Fax: 0098-0261-4418156Search for more papers by this authorParisa Ziaei
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran
Search for more papers by this authorAbstract
1,2-Disubstituted benzimidazoles are selectively synthesized in high yields under extremely mild conditions via the condensation of o-phenylenediamine derivatives with aldehyde derivatives using catalytic amount of iron(III) phosphate under solvent-free conditions. The use of readily available iron(III) phosphate as a reusable and recyclable catalyst makes this process quite simple, convenient, and environment-friendly.
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