A Convenient Synthesis of 2-Arylnaphtho[1,2-d]oxazole Derivatives Promoted by Triethylamine
Hong LI
Henan Key Laboratory of Chemical Biology and Organic Chemistry, and Key Laboratory of Applied Chemistry of Henan Universities, Department of Chemistry, Zhengzhou University, Zhengzhou, Henan 450052, China
Search for more papers by this authorKun WEI
Henan Key Laboratory of Chemical Biology and Organic Chemistry, and Key Laboratory of Applied Chemistry of Henan Universities, Department of Chemistry, Zhengzhou University, Zhengzhou, Henan 450052, China
Search for more papers by this authorHong LI
Henan Key Laboratory of Chemical Biology and Organic Chemistry, and Key Laboratory of Applied Chemistry of Henan Universities, Department of Chemistry, Zhengzhou University, Zhengzhou, Henan 450052, China
Search for more papers by this authorKun WEI
Henan Key Laboratory of Chemical Biology and Organic Chemistry, and Key Laboratory of Applied Chemistry of Henan Universities, Department of Chemistry, Zhengzhou University, Zhengzhou, Henan 450052, China
Search for more papers by this authorAbstract
A variety of 2-arylnaphtho[1,2-d]oxazole derivatives were efficiently synthesized in moderate to high yields by the reaction of aromatic aldehydes with 1-amino-2-naphthol derivatives in the presence of triethylamine in refluxing ethanol in air. Seven new 2-arylnaphtho[1,2-d]oxazole derivatives were obtained and characterized by the spectral data and elemental analysis. In addition, the X-ray crystal structures of 2-[4-(N,N-dimethylamino)phenyl]naphtho[1,2-d] oxzole (3d) and 1,1′-bis(naphtho[1,2-d]oxazol-2-yl)ferrocene (3n) have been determined.
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