A Facile Approach to Synthesis of the Di-O-methyl Ethers of (−)-Agatharesinol, (−)-Sugiresinol, (+)-Nyasol and (+)-Tetrahydronyasol
Wei-Guo Quan
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorBin-Xun Yu
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorJi-Yong Zhang
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorQi-Ren Liang
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorYong-Quan Sun
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorXue-Gong She
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, China
Tel.: 0086-0931-8912407; Fax: 0086-0931-8912582
Search for more papers by this authorXin-Fu Pan
Search for more papers by this authorWei-Guo Quan
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorBin-Xun Yu
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorJi-Yong Zhang
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorQi-Ren Liang
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorYong-Quan Sun
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
Search for more papers by this authorXue-Gong She
State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, China
Tel.: 0086-0931-8912407; Fax: 0086-0931-8912582
Search for more papers by this authorXin-Fu Pan
Search for more papers by this authorAbstract
The facile enantioselective synthesis of the di-O-methyl ethers of (−)-agatharesinol (1b), (−)-sugiresionl (2b), (+)-nyasol (3b) and (+)-tetrahydronyasol (4) were achieved in high yield. The absolute configuration of (+)-3a was confirmed via first total synthesis of (+)-3b and (+)-4.
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