Volume 22, Issue 7 pp. 761-763
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Synthesis, characterization and the effect of glucose-lowering of guanidino acid oxovanadium(IV) complexes

Ju-Tao Liu

Ju-Tao Liu

Faculty of Chemistry, Northeast Normal University, Changchun, Jilin 130024, China

Key Laboratory of Rare Earth Chemistry and Physics, Changchun institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China

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Xiao-Hong Wang

Xiao-Hong Wang

Faculty of Chemistry, Northeast Normal University, Changchun, Jilin 130024, China

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Jian-Xin Li

Jian-Xin Li

Faculty of Chemistry, Northeast Normal University, Changchun, Jilin 130024, China

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Jing-Fu Liu

Jing-Fu Liu

Faculty of Chemistry, Northeast Normal University, Changchun, Jilin 130024, China

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First published: 26 August 2010
Citations: 4

Abstract

Two guanidino acid oxovanadium(IV) complexes have been synthesized. Preliminary tests in vivo have shown that the two title complexes all display lowering glucose activity in vivo to STZ-rats. The effect of glucose-lowering of guanidino acetic acid oxovanadium(IV) complex in vivo is higher than that of guanidino propanoic acid oxovanadium(IV) complex.

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