Synthesis, structure and biological activities of novel triazole compounds containing N,N-dialkyldithiocarbamate moiety
Abstract
The two compounds, 2, 2-dimethy1-4-S-(N,N- dimethyldithiocarbamato)-5-(1, 2, 4-triazol-1-yl)-propione (1) and 2, 2-dimethyl-4-S-(N,N,-diethyldithiocarbamato)-5-(1, 2, 4-triazol-1-yl)-3-propione (2), were prepared by reacting N,N-dialkyldithiocarbamate sodium with 2, 2-dimethyl-4-bromo-5-(1, 2, 4-triazol-l-yl)-propione. Their structures were identified by elemental analysis, IR and 1H NMR spectroscopy. The structure of 1 has been determined by X-ray single crystal structure analysis. It crystallizes in monoclinic system with space group P21/c, a=1. 2315(3) nm, b=1.2057(2) nm, c =1.2532(3) nm, β=118.55(3)°, 2=4, V=1.6345(6) nm3, Dc=1.221 g/cm3, p=0.324 mm −1, F(000)=640. final R1 =0.0449. There is obvious potentially weak C-H···N intermolecular interaction in the crystal, which stabilizes the crystal structure. The result of the biological test showed that the two compounds have fungistasis and plant growth regulating activities.
