A Study on Some Copper (II) Complexes of Polyaza Cryptands and Planar Macrocycles—Synthesis, Characterization and Superoxide Dismutase Activity
Abstract
Two kinds of macrocyclic copper(II) complexes were synthesized. One of them is composed of copper(II) cryptates of ligands L1-L4 which are condensation products of 5-R-2-methoxy-1,3-phenyldialdehyde (R=OCH3, L1) with tris(2-aminoethyl) amine and 5-R-2-methothoxy-1, 3-phenyldialdehyde (R= CH3, L3) with tris(2-aminopropyl)amine as well as their reduced products of L1 and L3 (L2 and L4). The other is composed of two-dimensional macrocyclic copper(II) complexes of ligands L5-L8 of condensation products of diethylene triamine with 4-R-l-methoxy-2,6-phenyldialdehyde (R= Cl, Br. CH3, OCH3). The relationship between their structures and superoxide dismutase (SOD) activity was investigated. The results can provide some clues to the synthesis of SOD mimics.
