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Development of Pesticides Based on Phytoalexins.: Part 1: Design and Synthesis of Flavanone Analogues via Bioisosterism Substitution
Abstract
In order to search for novel fungicides with high activity, a series of 2-heteroaryl-4-chromanones were designed and synthesized via bioisosterism substitution. The structures of all new compounds were confirmed by spectroscopic methods and microanalyses. Preliminary bioassays indicated that some compounds showed fungicidal activity against Rhizoctonia solani, Fusarium oxysporum, Physalospora piricola and Cercospora beticola.
