Study on potassium bromodifluoroacetate Convenient approaches to the syntheses of trifluoromethylated compounds
Abstract
Treatment of potassium bromodifluoroacetate (1) with alkyl halides in the presence of copper, iodide and potassium fluoride in DMF at 85–0OTC for 3–5h gavethe trifluoromethylated derivatives in moderate to high yields.