Volume 11, Issue 4 pp. 366-369
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Study on potassium bromodifluoroacetate Convenient approaches to the syntheses of trifluoromethylated compounds

Heng-Duo U

Heng-Duo U

Zhejang Normal University, Jinghua, Zhejiang 321004

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Jian-Xing Duan

Jian-Xing Duan

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200033

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De-Bao Su

De-Bao Su

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200033

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Qing-Yun Chen

Corresponding Author

Qing-Yun Chen

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200033

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200033Search for more papers by this author
First published: July 1993
Citations: 9

Abstract

Treatment of potassium bromodifluoroacetate (1) with alkyl halides in the presence of copper, iodide and potassium fluoride in DMF at 85–0OTC for 3–5h gavethe trifluoromethylated derivatives in moderate to high yields.

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