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Synthesis of perfluoroalkyl-containing steroidal glycosides†
Wei-Yuan Huang,
Long Lü,
Corresponding Author
Wei-Yuan Huang
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032Search for more papers by this authorLong Lü
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
Search for more papers by this authorWei-Yuan Huang,
Long Lü,
Corresponding Author
Wei-Yuan Huang
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032Search for more papers by this authorLong Lü
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
Search for more papers by this author†
Dedicated to Professor Huang, Yao-Zeng on the occasion of his 80th birthday.
Abstract
A new kind of fluorine-containing amphiphiles — perfluoroalkyl-containing steroidal glycosides were synthesized in good yield through perfluoroalkylation by means of sodium dithionite-initiated addition of RFI to olefinic system. Preliminary study showed that these glycosides could form vesicles in aqueous medium as observed by electron microscopy.
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