Studies on sulfinato-dehalogenation: XI. Sodium dithionite-initiated perfluoroalkylation of electron-rich aromatic

The intermediary perfluoroalkyl radical generated from the reaction of perfluoroalkyl iodide with sodium dithionite was shown to be reactive toward phenols and aromatic amines, and resulted in the formation of a mixture of ortho- and para-substituted products. Thus, the reaction provides a new method for the synthesis of ortho- and para-perfluoroalkyl substituted phenols and anilines.