Volume 33, Issue 16
Heterocyclic Compounds
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ChemInform Abstract: A Facile Synthesis of (-)-4-Phenylsulfonyl-2-azetidinone.

Kee-In Lee

Kee-In Lee

Bio-Org. Sci. Div., Korea Res. Inst. Chem. Technol., Taejon 305-600, S. Korea

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Taek-Hyun Yoon

Taek-Hyun Yoon

Bio-Org. Sci. Div., Korea Res. Inst. Chem. Technol., Taejon 305-600, S. Korea

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Young-Key Shim

Young-Key Shim

Bio-Org. Sci. Div., Korea Res. Inst. Chem. Technol., Taejon 305-600, S. Korea

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Wan-Joo Kim

Wan-Joo Kim

Bio-Org. Sci. Div., Korea Res. Inst. Chem. Technol., Taejon 305-600, S. Korea

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First published: 22 May 2010
Citations: 1

Abstract

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ChemInform Abstract

A novel stereoselective synthesis of the title azetidinone (XI), a versatile intermediate for carbapenem synthesis, involving the diastereoselective cycloaddition of alkene (VII) across the C=N double bond of isocyanate (VIII) as key step is developed.

chemical structure image

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