ChemInform Abstract: A Facile Synthesis of (-)-4-Phenylsulfonyl-2-azetidinone.
Abstract
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ChemInform Abstract
A novel stereoselective synthesis of the title azetidinone (XI), a versatile intermediate for carbapenem synthesis, involving the diastereoselective cycloaddition of alkene (VII) across the C=N double bond of isocyanate (VIII) as key step is developed.