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ChemInform Abstract: Pyrimidinylimidazole Inhibitors of p38: Cyclic N-1 Imidazole Substituents Enhance p38 Kinase Inhibition and Oral Activity.
First published: 22 May 2010
Abstract
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ChemInform Abstract
The compounds (I) and (II) provide evidence supporting the potential therapeutic utility of p38 inhibitors in the treatment of rheumatoid arthritis, stroke, pulmonary inflammatory disease and virally induced inflammation.
