Volume 32, Issue 45
Heterocyclic Compounds
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ChemInform Abstract: Neutral Inhibitors of the Serine Protease Factor Xa.

William D. Shrader

William D. Shrader

Dep. Med. Chem., Axys Pharm. Inc., South San Francisco, CA 94080, USA

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Wendy B. Young

Wendy B. Young

Dep. Med. Chem., Axys Pharm. Inc., South San Francisco, CA 94080, USA

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Paul A. Sprengeler

Paul A. Sprengeler

Dep. Med. Chem., Axys Pharm. Inc., South San Francisco, CA 94080, USA

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Joan C. Sangalang

Joan C. Sangalang

Dep. Med. Chem., Axys Pharm. Inc., South San Francisco, CA 94080, USA

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Kyle Elrod

Kyle Elrod

Dep. Med. Chem., Axys Pharm. Inc., South San Francisco, CA 94080, USA

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Grant Carr

Grant Carr

Dep. Med. Chem., Axys Pharm. Inc., South San Francisco, CA 94080, USA

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First published: 23 May 2010

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract

Identification of lead compound (I) as factor Xa inhibitor and a binding mode model of (I) opens the way for further investigation of novel blood coagulation cascade inhibitors.

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