ChemInform Abstract: Syntheses of the L-manno and Some Other Analogues of the Terminal Determinants of the O-PS of Vibrio cholerae O:1.
Abstract
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ChemInform Abstract
A series of new analogues [cf. (IX)] of the upstream terminal monosaccharides of the two serotypes of V. cholerae O:1 is synthesized to get more information about the interaction with anti V. cholerae O:1 antibodies. The synthetic ligands differ from the end-groups in the natural V. cholerae O:1 O-specific polysaccharides in the anomeric or absolute configuration of perosamine, the nature of the amide group, or in the position of the methyl group in the D-perosamine moiety.
