Volume 32, Issue 18
Natural Products
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ChemInform Abstract: Synthesis of Optically Pure N-Boc-protected (2R,3R)- and (2R,3S)-3-Fluoroprolines.

Luc Demange

Luc Demange

Dep. Ing. Etud. Proteines, Cent. Etud. Saclay, F-91191 Gif-sur-Yvette, Fr.

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Jerome Cluzeau

Jerome Cluzeau

Dep. Ing. Etud. Proteines, Cent. Etud. Saclay, F-91191 Gif-sur-Yvette, Fr.

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Andre Menez

Andre Menez

Dep. Ing. Etud. Proteines, Cent. Etud. Saclay, F-91191 Gif-sur-Yvette, Fr.

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Christophe Dugave

Christophe Dugave

Dep. Ing. Etud. Proteines, Cent. Etud. Saclay, F-91191 Gif-sur-Yvette, Fr.

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First published: 27 May 2010

Abstract

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ChemInform Abstract

Starting from (2S,3S)-3-hydroxyproline derivatives such as (I) and (III), the N-Boc-protected optically pure target compounds are prepared as novel probes for studying the cis/trans isomerization of the amino acyl-proline peptide bond.

chemical structure image

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