ChemInform Abstract: Synthesis of Optically Pure N-Boc-protected (2R,3R)- and (2R,3S)-3-Fluoroprolines.
Abstract
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ChemInform Abstract
Starting from (2S,3S)-3-hydroxyproline derivatives such as (I) and (III), the N-Boc-protected optically pure target compounds are prepared as novel probes for studying the cis/trans isomerization of the amino acyl-proline peptide bond.