ChemInform Abstract: A Novel Bisnorditerpenelactone from Mikania hirsutissima.
Abstract
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ChemInform Abstract
The novel bisnorkaurenic acid-type diterpenelactone (I) (mikanialactone) is isolated from the aerial parts of M. hirsutissima besides five known kaurenic acid-type diterpenes. Kaurenic acid, a major component of this plant, and (I) display inhibitory activity on the proliferation of peripheral blood lymphocytes, while some of the remaining compounds slightly increase the proliferation.