Heterocyclic Compounds
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ChemInform Abstract: Heterocyclic Substituted Anthralin Derivatives as Inhibitors of Keratinocyte Growth and Inducers of Differentiation.
First published: 27 May 2010
Abstract
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ChemInform Abstract
A number of heterocyclic substituted derivatives [cf. (III), (V)] of antipsoriatic anthralin are synthesized and evaluated for their biological activity. Indole analogue (IIIa) shows potent antiproliferative activity combined with the ability to induce keratinocyte differentiation.
