ChemInform Abstract: Fluoride Ion-Mediated Intramolecular Aldol Cyclization of 7-(t-Butyldimethylsiloxy)-7-octenal.
Abstract
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ChemInform Abstract
A successful method for the preparation of eight-membered rings by fluoride ion mediated intramolecular aldol cyclization leads to the key intermediate (XI) of taxol and to ring systems, e.g. (XIII).