ChemInform Abstract: Asymmetric Conjugate Additions of Chiral Phosphonamide Anions to α,β-Unsaturated Carbonyl Compounds. A Versatile Method for Vicinally Substituted Chirons.
Abstract
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ChemInform Abstract
The title reaction proceeds with high regio- and stereoselectivity. Up to three stereogenic centers including in some cases quaternary C-atoms can be generated in a one-pot sequence.