Volume 31, Issue 51
Organoelement Compounds
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ChemInform Abstract: Asymmetric Conjugate Additions of Chiral Phosphonamide Anions to α,β-Unsaturated Carbonyl Compounds. A Versatile Method for Vicinally Substituted Chirons.

Stephen Hanessian

Stephen Hanessian

Dep. Chem., Univ. Montreal, Montreal, Que. H3C 3J7, Can.

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Arthur Gomtsyan

Arthur Gomtsyan

Dep. Chem., Univ. Montreal, Montreal, Que. H3C 3J7, Can.

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Nadia Malek

Nadia Malek

Dep. Chem., Univ. Montreal, Montreal, Que. H3C 3J7, Can.

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First published: 31 May 2010

Abstract

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ChemInform Abstract

The title reaction proceeds with high regio- and stereoselectivity. Up to three stereogenic centers including in some cases quaternary C-atoms can be generated in a one-pot sequence.

chemical structure image

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