Heterocyclic Compounds
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ChemInform Abstract: Synthesis and Biological Evaluation of Novel Piperidine Carboxamide Derived Calpain Inhibitors.
First published: 31 May 2010
Abstract
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ChemInform Abstract
The novel title compounds (VI) show good inhibitory activity of calpain and are found to be also active as inhibitors of NMDA induced convulsion in mice. It is found that calpain inhibition in brain reduces convulsions (no yields given).
