Preparative Organic Chemistry
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ChemInform Abstract: Synthesis and Biological Resolution of Condensed Bicyclic Isoparaconic Acid Derivatives.
First published: 31 May 2010
Abstract
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ChemInform Abstract
The kinetic resolution of readily prepared ester (V) is best achieved with immobilized lipase Lipozyme®. At low conversion value, acid (VI) is isolated with 84% e.e., whereas at high conversion value the resolved ester (V) is isolated with 98% e.e.
