Volume 31, Issue 43
Natural Products
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ChemInform Abstract: A New Enantioselective Synthesis of (2S)-Pipecolic Acid.

Claude Agami

Claude Agami

Lab. Synth. Asymetrique, CNRS, Univ. P. et M. Curie, F-75005 Paris, Fr.

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Catherine Kadouri-Puchot

Catherine Kadouri-Puchot

Lab. Synth. Asymetrique, CNRS, Univ. P. et M. Curie, F-75005 Paris, Fr.

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Jean-Claude Kizirian

Jean-Claude Kizirian

Lab. Synth. Asymetrique, CNRS, Univ. P. et M. Curie, F-75005 Paris, Fr.

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First published: 01 June 2010

Abstract

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ChemInform Abstract

A new route to enantiomerically pure pipecolic acid (XIII) involving the intramolecular cyclization between the vinylsilane moiety and the iminium ion generated from aminothioether (VIII) as the key step is described.

chemical structure image

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