Volume 31, Issue 23
Natural Products
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ChemInform Abstract: New Stereoselective Route to the Epoxyquinol Core of Manumycin-Type Natural Products. Synthesis of Enantiopure (+)-Bromoxone, (-)-LL-C10037α, and (+)-KT 8110.

Oliver Block

Oliver Block

Fachbereich Chem., Bergische Univ.-GH, D-42119 Wuppertal, Germany

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Georg Klein

Georg Klein

Fachbereich Chem., Bergische Univ.-GH, D-42119 Wuppertal, Germany

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Hans-Josef Altenbach

Hans-Josef Altenbach

Fachbereich Chem., Bergische Univ.-GH, D-42119 Wuppertal, Germany

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David J. Brauer

David J. Brauer

Fachbereich Chem., Bergische Univ.-GH, D-42119 Wuppertal, Germany

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First published: 08 June 2010

Abstract

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ChemInform Abstract

The key step in the synthesis of the title compounds (VI), (X), and (XI) is the enzymatic resolution of the diacetate (II).

chemical structure image

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