ChemInform Abstract: A Versatile Method for the Preparation of 2,2-Disubstituted Morpholine Analogues.
Abstract
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ChemInform Abstract
A novel two-step methodology for the preparation of 2,2-disubstituted morpholine analogues (IV) via iodoetherification is described. The application of this method allows the synthesis of the key intermediate (IVe) of a tachykinin receptor antagonist.