Isocyclic Compounds
Full Access
ChemInform Abstract: An Expedient Total Synthesis of cis-(+)-Sertraline from D-Phenylglycine.
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
An efficient and practical total synthesis of (+)-sertraline (VI) involving stereoselective intramolecular Friedel—Crafts cyclization (diastereoselectivity: 80%) is described starting from chiral pool D-phenylglycine.
