Heterocyclic Compounds
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ChemInform Abstract: Regioselective Reaction: Synthesis and Biological Activity of Some Mannich Derivatives.
First published: 09 June 2010
Abstract
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ChemInform Abstract
The Mannich reaction of easily available Schiff bases (III) appears to be highly regioselective and furnishes exclusively the N-Mannich bases (VI) (16 examples) and none of the S-Mannich base derivatives. The majority of the Mannich bases obtained show significant antifungal activity.
