Isocyclic Compounds
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ChemInform Abstract: New NO Donors with Antithrombotic and Vasodilating Activities. Part 28. N-(1-Cyanoalkyl)-N-hydroxyureas.
First published: 09 June 2010
Abstract
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ChemInform Abstract
A variety of new hydroxyureas (III) (14 examples) comprising aliphatic and aromatic substituents are synthesized and evaluated for their antithrombotic effects. It is established that the cyano group is essential for the desired activities as well as NO formation.
