Volume 31, Issue 16
Isocyclic Compounds
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ChemInform Abstract: Synthesis of Aryl α-Keto-acids via the Cu-Catalyzed Conversion of Aryl Nitroaldol Products.

Milind D. Nikalje

Milind D. Nikalje

Div. Process Dev., Natl. Chem. Lab., Pune 411 008, India

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Iliyas Sayyed Ali

Iliyas Sayyed Ali

Div. Process Dev., Natl. Chem. Lab., Pune 411 008, India

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Gajanan K. Dewkar

Gajanan K. Dewkar

Div. Process Dev., Natl. Chem. Lab., Pune 411 008, India

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A. Sudalai

A. Sudalai

Div. Process Dev., Natl. Chem. Lab., Pune 411 008, India

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First published: 09 June 2010

Abstract

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ChemInform Abstract

Cu(II)-catalyzed air oxidation of aryl nitroaldol products affords aryl α-keto acids (III) in good yields. In some cases such as (III), α-ketoaldehydes are obtained. Aliphatic substrates (V) react with the solvent methanol to give ethers (VII).

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