ChemInform Abstract: Efficient Syntheses of Cyclopropylacetylene, a Crucial Synthetic Intermediate for Efavirenz (DMP-266) (IV).
Abstract
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ChemInform Abstract
A cost effective and industrially scalable one-pot route for the synthesis of cyclopropylacetylene (III) via dichloride (II) is detailed. The desired acetylene (III) is obtained free from known side products.