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ChemInform Abstract: Structure and Antimalarial Activity of Adducts of 11-Azaartemisinin with Conjugated Terminal Acetylenes.
First published: 10 June 2010
Abstract
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ChemInform Abstract
Several N-substituted azaartemisinins are prepared in high yield and tested for their antimalarial activities. Compounds (IIIa) and (IIIb) are more effective than artemisinin against two drug-resistant strains of Plasmodium falciparum (no yields given).
