Heterocyclic Compounds
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ChemInform Abstract: Cage Dimeric N-Acyl- and N-Acyloxy-4-aryl-1,4-dihydropyridines as First Representatives of a Novel Class of HIV-1 Protease Inhibitors.
First published: 10 June 2010
Abstract
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ChemInform Abstract
Two different procedures are developed to prepare title compounds starting either from dihydropyridine (I) to yield (IV) or by modification of cage dimer (V) to give (VII). This new non-peptidic class of title compounds shows promising inhibitory activity of HIV-1 protease.
