Volume 31, Issue 5
Heterocyclic Compounds
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ChemInform Abstract: A Convenient Synthesis of Functionalized Vinylepoxides.

P. Veeraraghavan Ramachandran

P. Veeraraghavan Ramachandran

Brown and Wetherill Lab. Chem., Purdue Univ., West Lafayette, IN 47907, USA

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Marek P. Krzeminski

Marek P. Krzeminski

Brown and Wetherill Lab. Chem., Purdue Univ., West Lafayette, IN 47907, USA

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First published: 11 June 2010

Abstract

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ChemInform Abstract

The title compounds (IV) and (VII) are easily prepared by vinylalumination of α-bromoaldehydes and -ketones (I) and (V) and cyclization of the bromohydrins (III) and (VI). These epoxides [cf. (VIIa)] undergo typical reactions without affecting the vinyl group.

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