Heterocyclic Compounds
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ChemInform Abstract: Macrocyclic Bisindolylmaleimides: Synthesis by Inter- and Intramolecular Alkylation.
First published: 20 June 2010
Abstract
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ChemInform Abstract
Intermolecular alkylation is found to be superior over the intramolecular one in the preparation of the title compounds, e.g. (III), key precursors for the synthesis of macrocyclic competitive reversible inhibitors of the protein kinase C β1 and β2 isoforms.
