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ChemInform Abstract: Synthesis and Antiviral Activity of 5-Ethyl-5-halo-6-alkoxy- (or Azido)-5,6-dihydro-2′-deoxyuridine Diastereomers as Potential Prodrugs to 5-Ethyl-2′-deoxyuridine.
First published: 24 June 2010
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
Starting from the known potent HSV- inhibitor (I) some derivatives are prepared in a simple procedure. Among them nucleosides (III) and (IV) are found to be more potent than the parent compound (I) besides low cell cytotoxicity.
