ChemInform Abstract: Synthesis of Some Acridone Alkaloids and Related Compounds.
Abstract
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ChemInform Abstract
The previously reported four-step synthesis of acridinediones (I) is extended by an efficient aromatization with Pd—C leading to 1-hydroxyacridones (II). This new method, along with demethylation with HBr [concomitant loss of the ester group in (IIb)], provides a useful route to various methoxy- and hydroxy-substituted acridones.