Volume 29, Issue 1
Natural Products
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ChemInform Abstract: Versatile Synthesis of myo-Inositol Phospholipid Precursors.

S. J. A. GROVE

S. J. A. GROVE

Cambridge Cent. Mol. Recognit., Univ. Chem. Lab., Cambridge CB2 1EW, UK

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I. H. GILBERT

I. H. GILBERT

Cambridge Cent. Mol. Recognit., Univ. Chem. Lab., Cambridge CB2 1EW, UK

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A. B. HOLMES

A. B. HOLMES

Cambridge Cent. Mol. Recognit., Univ. Chem. Lab., Cambridge CB2 1EW, UK

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G. F. PAINTER

G. F. PAINTER

Cambridge Cent. Mol. Recognit., Univ. Chem. Lab., Cambridge CB2 1EW, UK

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M. L. HILL

M. L. HILL

Cambridge Cent. Mol. Recognit., Univ. Chem. Lab., Cambridge CB2 1EW, UK

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First published: 24 June 2010

Abstract

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ChemInform Abstract

Homochiral myo-inositol derivatives like (VI), possessing either the natural or unnatural ring stereochemistry for inositol phospholipids, are synthesized from racemates (II) using camphor acetals, e.g. (III), in a resolution—protection sequence.

chemical structure image

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