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ChemInform Abstract: Preparation of (S)-Piperazine-2-carboxylic Acid, (R)-Piperazine-2-carboxylic Acid, and (S)-Piperidine-2-carboxylic Acid by Kinetic Resolution of the Corresponding Racemic Carboxamides with Stereoselective Amidases in Whole Bacterial Cells.
First published: 24 June 2010
Abstract
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ChemInform Abstract
The title investigation is presented with a view to the importance of non-proteinogenic amino acids as precursors of various pharmacologically active compounds. Racemic carboxamides (I) and (III) are prepared by hydrogenation of the corresponding heteroaromates.
