Heterocyclic Compounds
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ChemInform Abstract: Chemical and Biological Properties of 5-Indolones.
First published: 24 June 2010
Abstract
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ChemInform Abstract
Michael-type addition leads to the title compounds, e.g. (III) and (IV). This addition is reversible meaning that these compounds behave as prodrugs of cytotoxic indolones. The prepared derivatives show good cytotoxicity and in some cases also antibacterial activity.
