ChemInform Abstract: 1,7-Migration of Benzyl Group in 2-Substituted N-Benzylindoles.
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
The reaction of ketone derivatives (I) with 1-phenyl-1-benzylhydrazine (II) gives the corresponding N-benzylindoles, which undergo subsequent debenzylation or 1,7-migration of the benzyl group in PPA above 100 °C to afford products (III) and (IV), respectively. The hydrazone intermediates [cf. (V)] as well as the N-benzylindoles [cf. (VI)] can be isolated under milder conditions.
