Volume 29, Issue 1
Heterocyclic Compounds
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ChemInform Abstract: Diastereoselective Enolsilane Coupling Reactions.

S. J. MILLER

S. J. MILLER

Dep. Chem., Boston Coll., Chestnut Hill, MA 02167, USA

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C. D. BAYNE

C. D. BAYNE

Dep. Chem., Boston Coll., Chestnut Hill, MA 02167, USA

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First published: 24 June 2010

Abstract

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ChemInform Abstract

Some trans-substituted succinimides (II) are formed by treatment of hydrazides (I) with silyl triflate and amine. A reaction mechanism via intramolecular coupling of intermediate bis(enolsilanes) is proposed. In addition, a new reaction of azidoacetate derivatives (III) is presented that results in the exclusive formation of trans pyridazine derivatives (IV).

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