Volume 29, Issue 1
Preparative Organic Chemistry
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ChemInform Abstract: A Mild and Efficient Method for Selective Cleavage of Ketals and Acetals Using Lithium Chloride in Water—Dimethyl Sulfoxide.

P. K. MANDAL

P. K. MANDAL

Dep. Org. Chem., Indian Assoc. Cultiv. Sci., Jadavpur, Calcutta 700 032, India

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P. DUTTA

P. DUTTA

Dep. Org. Chem., Indian Assoc. Cultiv. Sci., Jadavpur, Calcutta 700 032, India

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S. C. ROY

S. C. ROY

Dep. Org. Chem., Indian Assoc. Cultiv. Sci., Jadavpur, Calcutta 700 032, India

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First published: 24 June 2010

Abstract

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ChemInform Abstract

An efficient method for the cleavage of acetals and ketals under mild and neutral conditions using LiCl/H2O in DMSO at elevated temperatures is reported. Aryl and α,β-unsaturated compounds cleave readily, diaryl and saturated educts remain unaffected.

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