Preparative Organic Chemistry
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ChemInform Abstract: Reaction of 2-Phenylaminothiazoline with α-Haloketones.
First published: 24 June 2010
Abstract
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ChemInform Abstract
The reaction of α-haloketones (II) with aminothiazoline (I) proceeds regioselectively by attack of the halide at the exocyclic nitrogen atom of the aminothiazoline (I) to give the imidazo[2,1-b]thiazolinium bromides (III). The structure of the bromides is supported by spectroscopic and chemical methods.
